Aunt May has been kidnapped, and it is up to Spider-Man to save the day. But little does he know that Doc Ock has brought together the Sinister Six, six of the worst villains around, and is ready to end Spidey's life for good.

Roam 18 levels of New York City using all of Spider-Man's powers like the Spidey Armour, spin kick, Spidey's trusty webbing and his wall crawling abilities. Your main aim is to rescue Aunt May, but you can kick some evil guys along the way if you wish.

The game is side-scrolling action consisting of two exploration levels followed by a boss battle (in order, Mysterio, Sandman, Vulture, Scorpion, Kraven the Hunter, and Doctor Octopus). Some levels require collecting keys to unlock doors to reach new areas.