Swamp Thing is based on the DC comic of the same name. Deep in the swamps of Louisiana, a Dr. Holland, is hard at work on a growth formula for plants. His sponsor however has different ideas for the technology and burns down the lab. The poor doctor is burned and covered with formula and inside of the organically rich Bayou swamps... he becomes Swamp Thing.

The game is a side-scrolling platform game. Swamp Thing can punch (but not duck and punch) and jump a short distance. Health power-ups will be needed to keep him alive and additionally ball power-ups can be found to give him a projectile weapon.